The Latest on America's Most Wanted

New York/Florida Serial Rapist Capture: AMW has repeatedly profiled the story of a courageous homeless woman who fought off a man who was raping her and in the process, grabbed the chain that dangled around his neck. The New York Police Department's Manhattan Special Victim's Unit has been just as vigilant - working with the victim and trying to find out who that chain belonged to. Nearly two years later, that chain, and the DNA on it has led to the arrest of 43-year-old Louis Alfonso. Cops have charged him with rape and attempted murder in the New York case, and believe he's responsible for a number of other vicious attacks. This Saturday night, we’ll give you all the details on Alfonzo’s arrest.

William Greer: When America 's Most Wanted aired William Greer's story in July, tips flowed in like the Mississippi River . Tip after tip said the fugitive was in New Orleans , so cops are pounding the pavement in the French Quarter right now -- along with the AMW team.

Helen Hill Killer: In New Orleans , young filmmaker Helen Hill and her physician husband Paul were awakened by an intruder -- cops say the next thing they knew, he opened fire. According to police, Paul did the only thing he could, and acted as a human shield to protect his young son.

Pauley Perrette Update: This Saturday night, we’ll give you an update on AMW’s crime fighting partnership with NCIS star Pauley Perrette. Perrette teamed up with AMW to help investigators solve the murder of two young girls: Shannon Paulk in Prattville , Ala. and Raven Jeffries in Detroit . Perrette was touched by Shannon's story because of her own family ties to the Prattville area, so she donated a $10,000 reward to help catch Shannon 's killer.

School Safety: For many youths, going away to college brings about new responsibilities in their lives. Living away from home allows certain freedoms, but also exposes young adults to harsh new realities. This is particularly true when students begin living on their own away from campus. Students for the first time in their lives have to deal with things like paying the phone bill and making sure that rent is in on time. But it also means that they need to be much more aware of the potential dangers that exist once they leave the comfort and security of on-campus living.

Jennifer Birge: Jessica Birge is described as a sweet girl without an enemy in the world. But now, she's nowhere to be found. Police in Texas are looking for new clues in hopes of finding 25-year-old Birge, who went missing on Aug. 11, 2007. This week, join us in the search.